Pro-L-aminohexanoic acid
نویسندگان
چکیده
* Institut de Pharmacologie Moleculaire et Cellulaire, UPR 411 du CNRS, Universite de Nice Sophia Antipolis, 660 Route des Lucioles, Sophia Antipolis, 06560 Valbonne, France, t Laboratoire Structure des Proteines en Solution, Departement d'Ingenierie et d'Etude des Proteines, C.E.N. Saclay, 91191 Gif-sur-Yvette Cedex, France, and $Laboratory of Organic Chemistry, University of Athens, Athens, Greece.
منابع مشابه
Purification of human renin by affinity chromatography using a new peptide inhibitor of renin, H.77 (D-His-Pro-Phe-His-LeuR-Leu-Val-Tyr).
A new affinity column for renin was prepared by coupling the isosteric peptide inhibitor of renin, H.77 (D-His-Pro-Phe-His-LeuR-Leu-Val-Tyr, where R is a reduced isosteric bond, -CH2-NH-), to activated 6-aminohexanoic acid-Sepharose 4B. Chromatography of a crude extract of human kidney cortex on this material resulted in a 5500-fold purification of renin in 76% yield. The purified enzyme (speci...
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